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Dulaglutide Manufacturers In India

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Dulaglutide Injection

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Dulaglutide Manufacturers In India | Dulaglutide Third Party Manufacturing Pharma Companies

Dulaglutide Manufacturers In India - Because of the rising frequency of diabetes and the growing number of health-awareness programs launched by various health organizations, the type 2 diabetes market is mature and congested. This leads to a significant increase in the Dulaglutide medication market between 2021 and 2024, with the market more than doubling in size. If you are the one want to invest in the Dulaglutide drug market then PharmaHopers can help you. We have the list of some of the leading Dulaglutide Manufacturers In India.

Eli Lilly is developing Dulaglutide (LY2189265), a long-acting GLP-1 analog that is now in Phase III clinical trials. You may learn more about Dulaglutide by reading this article. Make your decision, then return to us for the top Dulaglutide Manufacturing businesses in India.

What is dulaglutide and how it is used?

  • Eli Lilly's Trulicity brand of dulaglutide is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist developed utilizing recombinant DNA technology.
  • It's been approved as a supplement to diet and exercise for the treatment of type 2 diabetes (T2DM).
  • Dulaglutide was approved by the FDA in 2014 for use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular events, and in February 2020 for use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular events.
  • Dulaglutide is a type of anti-diabetic drug.
  • It works by increasing pancreatic insulin release, lowering hormones that elevate blood sugar levels, slowing digestion, and decreasing appetite.
  • The injection of dulaglutide slows the passage of food through the stomach.

Uses of dulaglutide

  • In individuals with type 2 diabetes, dulaglutide is used in conjunction with diet and exercise to enhance blood sugar management.
  • Dulaglutide is also used to help persons with type 2 diabetes and heart disease who also have heart disease or are at risk of developing heart disease minimize their risk of significant heart problems including heart attack or stroke.
  • When diet and exercise alone do not give adequate blood sugar control in patients for whom metformin is inappropriate, this drug can be taken as a monotherapy (single therapy).
  • If needed, this treatment can be combined with other glucose-lowering medications as an add-on therapy.
  • Dulaglutide is not approved for the treatment of type 1 diabetes.
  • Dulaglutide can be used for a variety of other things not included in this medication guide.

Before Using dulaglutide

  • If you have an allergy to dulaglutide, any other drugs, or any of the ingredients in dulaglutide injection, tell your doctor.
  • Tell your doctor about any additional prescription and nonprescription medications, over-the-counter medications, vitamins, nutritional supplements, and herbal products you're using or planning to use. Because dulaglutide may alter the way your body absorbs medications, it's very important to tell your doctor about all the medications you take by mouth.
  • Tell your doctor if you have ever had renal disease, pancreatitis, stomach/intestinal abnormalities, or other difficulty digesting food; diabetic retinopathy, or if you have ever had kidney or liver illness.
  • It's unclear whether dulaglutide will cause harm to an unborn child. If the woman is pregnant or plans to become pregnant, tell her doctor.
  • Breastfeeding may not be safe while taking this medication. Inquire with your doctor about any potential risks.
  • In the event that you become ill, acquire an infection or fever, experience extraordinary stress, or are harmed, consult your doctor. These disorders can have an impact on your blood sugar levels and the amount of dulaglutide you require.
  • Dulaglutide is not recommended for people under the age of 18.
  • While taking this medication, you should avoid drinking alcohol because it can raise your risk of low blood sugar.
  • Visually inspect this medicine for particles or discoloration before usage. If either of these conditions exists in the medicine please call for new medicine and do not use the liquid.
  • One should clean the injection site with rubbing alcohol before injecting each dose of medicine. To reduce harm beneath the skin, change the injection site every time.

How should I use dulaglutide?

  • Before you start taking dulaglutide and every time you obtain a refill, read the Medication Guide and Instructions for Use carefully.
  • Dulaglutide injection is taken once a week and comes as a solution (liquid) in a prefilled dosage pen to inject subcutaneously (under the skin) in the stomach, thigh, or upper arm.
  • Dulaglutide should be taken on the same day each week at the same time. Allow at least 3 days between doses if you change your dosing day.
  • Dulaglutide is available as prefilled dosing pens that contain one dose of medicine. Never mix dulaglutide with any other drug; always inject it in its own prefilled dosage pen.
  • Dulaglutide can be taken with or without food.
  • If you're also on insulin, give the dulaglutide and insulin injections separately. Do not combine the two. These drugs can be injected into the same part of the body, but the injection sites should not be close together.
  • To receive the best benefit from this drug, take it on a daily basis. Use it on the same day each week to help you remember.
  • Follow your doctor's medication treatment regimen, food plan, and exercise program to the letter.
  • The dosage of the medicine is prepared by your doctor after seeing your medical condition and treatment response. To reduce the chance of stomach/abdominal side effects, your doctor will start you on a low dose and gradually raise it. Carefully follow your doctor's recommendations.

Common Side Effects of Dulaglutide:

  • diarrhea
  • nausea
  • heartburn
  • decreased appetite
  • feeling tired
  • indigestion
  • fatigue
  • constipation
  • gas
  • bloating
  • gastroesophageal reflux disease (GERD)
  • low blood sugar (hypoglycemia).

Serious Side Effects of Dulaglutide:

  • Persistent stomach pain that starts in the upper left or middle and spreads to the back
  • vomiting
  • hives
  • rash
  • itching
  • difficulty breathing or swallowing
  • swelling of tongue, lips, face, or throat
  • vision changes
  • fast heartbeat
  • pancreatitis
  • signs of a thyroid tumor
  • low blood sugar
  • kidney problems-
  • little or no urination

Storage and disposal of Dulaglutide

  • The pen should be kept in the fridge. If refrigeration isn't an option, keep your pen at room temperature (less than 30°C) for up to two weeks. Do not put it in the freezer.
  • Remember to keep this and all other medicines out of the reach of children, never share your medicines with others, and only use this medication as directed.
  • Do not flush the medicine in the toilet or into a drain directly. 
Dosage Inforation of Dulaglutide:

Dosage Forms & Strengths: It is Available in single-dose pen

  • 0.75mg/0.5mL
  • 1.5mg/0.5mL
  • 3mg/0.5mL
  • 4.5mg/0.5mL

Diabetes Mellitus Type 2

  • Initial: 0.75 mg SC once a week
  • To improve glycemic control, raise the dose to 1.5 mg once a week.
  • If you require more glycemic control, go up to 3 mg once a week after at least 4 weeks on the 1.5-mg dose.
  • After at least 4 weeks on the 3-mg dose, raise to a maximum dose of 4.5 mg once weekly if more glycemic control is required.
  • In people with type 2 diabetes mellitus, a once-weekly SC injection in addition to diet and exercise is recommended to enhance glycemic control.
  • It's also recommended for lowering the chance of serious cardiovascular problems.

PEDIATRIC: Consult your physician. Safety and efficacy have yet to be determined.

Dosage Modifications

  • There is no need to change the dosage if you have renal impairment of any kind.
  • Hepatic impairment (of any severity): No dosage change is necessary; caution is suggested due to insufficient data.

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