Top 43 Benfotiamine Manufacturers In India

Benfotiamine Manufacturers In India | Benfotiamine Third Party Manufacturing Company

Benfotiamine Manufacturers In India - The Benfotiamine manufacturing market seems to rise at a significant rate all through the years, between 2021 and 2025. In 2021, the market is rising with the growing choice of techniques through main key pharma players. If you are thinking of investing in the Benfotiamine manufacturing market then this is the time. Contact PharmaHopers for any queries related to Benfotiamine manufacturing plus we can provide you the Best list of  Benfotiamine Manufacturers In India.

Increased investments in research and development, as well as technological advancements in the Benfotiamine market, all contribute to market expansion.

Globally, Competitors pharma companies identified in the Benfotiamine manufacturing market include Pharmaffiliates, Hangzhou Eastbiopharm Co., Country Life, Hamari, Ltd, Ami Lifesciences, Prayosha Health Care, BioXera Pharma, Mascot, Neurohacker Collective, Basil Pharmaceuticals, Klaire, Kimia Biosciences Ltd, Kaival Chemicals, XY Mogen, and AOR. Other than these we can help you in providing the Top Benfotiamine Manufacturers In India. 

Some other details regarding the drug Benfotiamine is given below in this article. Read the blog and make your choice. Contact PharmaHopers for further information.

What is Benfotiamine and how it works?

Benfotiamine is known as a synthetic version of thiamine which is also recognized as vitamin B1. This vitamin is required for many of the human body’s functions and is more quickly absorbed through digestion. Gut enzymes (phosphatases) change benfotiamine, which is then broken down into thiamine by red blood cells or the liver.

Vitamin B1 is found in benfotiamine. This vitamin is required for the body to process carbohydrates, fats, and proteins. Vitamin B1 is required for the formation of adenosine triphosphate, the body's primary fuel (ATP). Benfotiamine provides the required amount of vitamin B1, which nerve cells require to function properly.

Benfotiamine was produced and invented in Japan. It is reported internationally by Wada, Takagi, Minakami, et al. in 1961.

Benfotiamine may work by:

• Activating transketolase, an enzyme that converts sugars into energy rather than harmful advanced glycation end-products in the pentose phosphate pathway (AGEs)
• Increasing cell regeneration and decreasing cell death by altering the production of specific enzymes
• Changing how energy is used in cells to promote healthy growth and prevent cancer
• Inflammation in brain cells and white blood cells is being reduced.
• The GSK3b gene is inhibited, which improves brain health.
• The NOX4 gene is inhibited, which improves sugar breakdown in muscles.

Uses of Benfotiamine

• The use of benfotiamine in the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus Type 2 has been studied.
• Benfotiamine may be especially beneficial for protecting the body from the harmful byproducts of too much sugar and improving diabetes and Alzheimer's disease symptoms, according to research.
• For 24 weeks, an AGEs inhibitor-containing benfotiamine and vitamins B6 and B12 reduced pain and inflammation.
• Benfotiamine improved mental function and reduced depression symptoms.
• Benfotiamine helps restore thiamin levels and stop deficiency symptoms like heart, nerve, and brain problems.
• Benfotiamine may prevent leukemia through a mechanism known as pyroptosis cell death, according to in vitro studies.
• Benfotiamine is a powerful antioxidant with anti-inflammatory properties that are produced by inhibiting the synthesis of prostaglandins and leukotrienes.
• It's used to treat numbness or weakness brought on by alcohol or smoking.
• It's also used to prevent retinopathy complications (infection of the retina which results in impairment or loss of vision)

Furthermore, some people believe that taking benfotiamine as a supplement can help with:

• Anxiety
• Back pain
• Depression
• Diabetic neuropathy
• FIbromyalgia
• Other types of neuropathy
• Sciatica
• Thyroid disease (like Hashimoto's disease)

General Information regarding Benfotiamine: 

• The Generic Name is Benfotiamine
• DrugBank Accession Number: DB11748
• Type: Small Molecule
• Groups: Approved, Experimental
• Synonyms: Benfotiamine; Benfotiamine; Benphothiamine; Benzoylthiamine monophosphate; S-benzoylthiamine monophosphate
• Associated Conditions: Thiamine Deficiency
• Therapeutic Classification: Vitamins

Before Using Benfotiamine

• It is not recommended to take Benfotiamine if the person is having an allergy to this medicine or Thiamine.
• There is no data found for this medicine about the safety of women during pregnancy. Women who is pregnant should avoid this medicine. Contact your health care specialist if you are pregnant or planning to pregnant
• There is no data found on whether Benfotiamine enters the mother's breast milk and is safe if you are lactating. Avoid this medicine if the mother is breastfeeding
• If you have any symptoms that could impair your ability to concentrate or drive, don't get behind the wheel.
• While taking this medication, stay away from alcohol. There isn't enough information about Benfotiamine's interaction with alcohol.
• If you're thinking about taking Benfotiamine, consult your doctor to find out how much you should take.
• Any medications or other supplements you're taking should be disclosed to your doctor. They can see if benfotiamine is interfering with the way your medications work.

How to use Benfotiamine

• Follow your doctor's instructions when taking this medication. Do not consume this medicine more or less than what your health care specialist has been prescribed.
• If you experience any unfavorable side effects, talk to your doctor. It is not recommended to stop taking this medicine without first talking to your doctor.
• Benfotiamine is available in the form of tablets or capsules from pharmaceutical companies. They can be packaged in blisters or plastic bottles, both of which are contained in cardboard packaging.
• The medicine can be taken orally with food or according to the doctor's instructions.
• This medicine is taken as a 300-600mg oral dose which is spread out throughout the day, usually taken in two divided doses with meals (150mg or 300mg twice daily).
• The length of the course and the daily dosage Depending on the severity of the diabetic neuropathy, the attending physician may prescribe benfotiamine.
• After a meal, benfotiamine should be taken.

Dosage information of Benfotiamine

• For patients suffering from painful peripheral diabetic neuropathy, one study found that 10 320 mg of benfotiamine daily was more effective than 150 mg benfotiamine daily.
• While there haven't been many reports of dangerous side effects, going up to extremely high doses isn't recommended due to a lack of research.
• In the case of diabetic neuropathy, the minimum daily dosage is 150 mg, and the maximum is 300 mg.
• In Alzheimer's patients with improved cognitive function, starting with a lower dose is a good strategy.
• If you're thinking about taking the supplement, talk to your doctor about what amount, if any, is right for you.
• The dose for children over the age of ten is much lower, at 30-35 mg per day.
• At doses of up to 600 mg daily for up to 24 weeks, benfotiamine is likely to be safe.

Side Effects of Benfotiamine:

• Upset stomach
• Nausea
• Dizziness
• Hair loss
• Body odor
• Decrease blood pressure
• Quincke edema
• Cough
• Difficulty in swallowing
• Itching
• skin rash
• Face, eyelids, lips, or tongue swell
• Difficulty in breathing
• Weight gain

Overdose, Missed Dose, and Storage Information related to Benfotiamine

• There is a scarcity of information on Benfotiamine overdose. Because the vitamin is fat-soluble, excess amounts are likely to be stored in the body. If you suspect an overdose, go to the nearest emergency room right away.
• If the patient forgets to take his/her dose of medicine, do so as soon as he/she remember. Benfotiamine should be kept at room temperature in a dark, dry place.
• This drug is not recommended for children. The expiration date will be 4 years if all rules are followed. Remember that using a medicine after it has passed its expiration date is strictly prohibited.

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