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Alogliptin Manufacturers In India

Alogliptin Tablets

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Alogliptin Tablets

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Alogliptin Manufacturers In India | Alogliptin Third Party Manufacturing Company

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Read the article to know more about the product Alogliptin, its uses, side effects, etc.

What is alogliptin and how it works?

  • Alogliptin is a selective, orally accessible inhibitor of dipeptidyl peptidase-4 enzymatic activity (DPP-4).
  • Alogliptin is made chemically as a benzoate salt and is mostly found as the R-enantiomer (>99 percent).
  • On January 25, 2013, the FDA authorized the medication.
  • Alogliptin is a type of anti-diabetic drug. It works by causing the pancreas to release more insulin and reducing the hormones that cause blood sugar levels to rise. As a result, fasting and post-meal sugar levels are lowered.
  • The combination of alogliptin and metformin can be taken alone or in conjunction with other medications, as well as a healthy diet and exercise.

Uses of Alogliptin

  • In individuals with type 2 diabetes, alogliptin is used in conjunction with diet and exercise to improve blood sugar management. Type 1 diabetes is not treated with alogliptin.
  • This medication is occasionally used in conjunction with other diabetes medicines.
  • Alogliptin can be used for a variety of other things not included in this pharmaceutical guide.
  • Patients with insulin-dependent diabetes or type 1 diabetes will not benefit from this medication.
  • Alogliptin is a drug that is used to treat hyperglycemia in people who have type 2 diabetes.

General Information:

  • The Generic name is alogliptin (AL oh GLIP tin)
  • Dosage forms mainly come in oral tablets (12.5 mg; 25 mg; 6.25 mg)
  • Drug class: Dipeptidyl peptidase 4 inhibitors
  • DrugBank Accession Number: DB06203
  • Type: Small Molecule
  • Groups: Approved
  • Synonyms: Alogliptin; Alogliptina; Alogliptine; Alogliptinum
  • Associated Conditions: Type 2 Diabetes Mellitus

What special precautions should you follow before using Alogliptin?

  • If you have an allergy to alogliptin, any other drugs, or any of the ingredients in alogliptin tablets, tell your doctor.
  • Tell your doctor about any prescription and over-the-counter medications, vitamins, nutritional supplements, and herbal products you're using or planning to use. Make careful to mention insulin and any diabetes meds.
  • If you have ever had comparable problems with your heart or pancreas, or if you have kidney or liver illness, alogliptin can cause serious adverse effects. Tell your health specialist about all your medical records.
  • Tell your doctor if you have ever had heart failure, pancreatitis, gallstones, or diabetic ketoacidosis before using this drug.
  • If you drink or have ever drunk a lot of alcohol, tell your doctor.
  • If a woman is pregnant or plans to become pregnant, follow your doctor's instructions for using this medicine. Call your doctor if you become pregnant while taking alogliptin.
  • Anyone under the age of 18 is not permitted to use alogliptin.
  • There are no good studies in women to determine the harm to an infant if this medicine is used while breastfeeding. Before taking this drug while nursing, talk to your doctor about the dangers.
  • Tell your doctor or dentist that you are taking alogliptin if you are having surgery, including dental surgery.
  • Consult your doctor for advice on what to do if you are injured or develop a fever or infection. These disorders may have an impact on your blood sugar levels and the amount of alogliptin you require.
  • Until you know how Alogliptin affects you, be cautious when driving or operating machinery.

How should Alogliptin be used?

  • Before you start taking alogliptin, read the Medication Guide issued by your pharmacist carefully, and then read it again each time you get a refill. Inquire with your doctor if you have any questions regarding the medicine.
  • Alogliptin is available as a tablet to be swallowed. Do not chew, split, or crush; swallow whole.
  • It is normally taken once a day, with or without food. Every day, around the same time, take alogliptin.
  • Do not take more or less of it, or take it more frequently than your doctor has suggested.
  • As recommended by your doctor, take this medication by mouth.
  • The medicine dose is restricted by your medical condition and treatment response. To get the best advantage from this medicine, take it on a regular basis.
  • Maintain strict adherence to your diabetes treatment plan, which includes medications, nutrition, and exercise.

Dosage Information:

Dosing Forms & Strengths consist of 

  • 12.5mg/15mg
  • 12.5mg/30mg
  • 12.5mg/45mg
  • 25mg/15mg
  • 25mg/30mg
  • 25mg/45mg

Colour information:

  • oval, biconvex, Light red, film-coated 25 mg tablets with "TAK ALG-25" imprinted on aside.
  • oval, biconvex, Yellow, film-coated 12.5 mg tablets with "TAK ALG-12.5" printed on aside.
  • 6.25 mg tablets are light pink, biconvex, film-coated, oval, and printed on one side with "TAK ALG-6.25".

Diabetes Mellitus Type 2

  • Follow your doctor's orders or the label's instructions. Indicated as a supplement to diet and exercise in individuals with type 2 diabetes mellitus to enhance glycemic control.
  • Starting dose is determined on the patient's current medication regimen.

Dosage Modifications

  • With NYHA Class 1 or II heart failure, the initial dose of pioglitazone should be limited to 15 mg per day.
  • Coadministration with strong CYP2C8 inhibitors (eg, gemfibrozil): Pioglitazone doses should not exceed 15 mg per day.

PEDIATRIC: Safety and efficacy have yet to be determined. Consult a professional pediatrician before using.

Common Side Effects of Alogliptin

  • headache
  • stuffy or runny nose
  • sore throat
  • Body pain
  • ear congestion
  • joint pain
  • Upper respiratory tract infection
Serious Side Effects of Alogliptin
  • severe abdominal pain that may go to your back
  • vomiting
  • excessive tiredness
  • loss of appetite
  • Stomach Pain in the upper right area
  • dark urine
  • yellowing of the skin or eyes
  • fever
  • blisters
  • heart problems
  • skin peeling
  • rash
  • hives
  •  inflammation of the pancreas
  • itching
  • swelling of the face, lips, eyes, tongue, or throat
  • a severe autoimmune reaction 
  • hoarseness
  • difficulty breathing or swallowing
  • shortness of breath when lying down
  • sudden weight gain

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